Table 4.
Cox proportional hazard regression analysis for association between covariables and kidney failure
| Variable | Univariable Analysis |
P | Multivariable Analysis |
P value |
|---|---|---|---|---|
| Hazard ratio (95% CI) | Hazard ratio (95% CI) | |||
| Age (per year increment) | 1.03 (1.01–1.07) | 0.009 | 1.04 (1.02–1.07) | 0.002 |
| Sex | 0.93 | |||
| Female | 1.00 (reference) | |||
| Male | 0.96 (0.46–2.03) | |||
| Type of IBD | 0.56 | |||
| Ulcerative colitis | 1.00 (reference) | |||
| Crohn’s disease | 1.25 (0.59–2.64) | |||
| Baseline eGFR (per ml/min increment) | 0.94 (0.92–0.97) | <0.001 | 0.94 (0.91–0.98) | 0.003 |
| Baseline UPCR (per 1 g/g increment) | 1.13 (1.06–1.21) | <0.001 | ||
| Total chronicity score (per grade increment) | 5.93 (3.24–10.85) | <0.001 | 4.01 (2.21–7.29) | <0.001 |
CI, confidence interval; eGFR, estimated glomerular filtration rate; IBD, inflammatory bowel disease; UPCR, urinary protein-to-creatinine ratio.
Number of events: 29.