(a) Kaplan Meier failure curves with stroke as outcome according to CKD status. (b) Kaplan Meier failure curves with MI as outcome. (c) Kaplan Meier failure curves with all-cause mortality as outcome.
Parameters included in the CKD stratified adjusted models:
Stroke: age, sex, smoking (never, former, and active), number of diseased vessels (none, diffuse coronary atherosclerosis without significant [>50%] stenosis/1, 2, or 3 vessel disease), atrial fibrillation (yes/no), diabetes (yes/no), statin treatment (yes/no), antiplatelet treatment (yes/no), antihypertensive drugs prescribed (0, 1, 2, or >2), and BMI category (kg/m2): (<18.5 [underweight], 18.5–24.9 [normal], 25–29.9 [overweight], 30–34.9 [class 1 obesity], 35–39.9 [class 2 obesity], ≥40 [class 3 obesity]).
MI: age, sex, smoking (never, former, and active), number of diseased vessels (none, diffuse coronary atherosclerosis without significant [>50%] stenosis/1, 2, or 3 vessel disease), diabetes (yes/no), hypertension (yes/no), statin treatment (yes/no), antiplatelet treatment (yes/no), and BMI category (kg/m2): (<18.5 [underweight], 18.5–24.9 [normal], 25–29.9 [overweight], 30–34.9 [class 1 obesity], 35–39.9 [class 2 obesity], ≥40 [class 3 obesity]).
All-cause mortality: age, sex, smoking (never, former, active), modified Charlson comorbidity index (0/1/2/>2), number of diseased vessels (none, diffuse coronary atherosclerosis without significant [>50%] stenosis/1, 2, or 3 vessel disease), and BMI category (kg/m2): (<18.5 [underweight], 18.5–24.9 [normal], 25–29.9 [overweight], 30–34.9 [class 1 obesity], 35–39.9 [class 2 obesity], ≥40 [class 3 obesity]). BMI, body mass index; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; 95% CI, 95% confidence interval.