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. 2023 Nov 19;9(2):370–382. doi: 10.1016/j.ekir.2023.11.008

Figure 1.

Figure 1

Microscopic features of typical ABBA. (a) Acute tubular injury with epithelial simplification, tubular dilatation, and interstitial edema (hematoxylin and eosin stain, original magnification 400x, scale bar = 20 μm). (b) Acute on chronic tubular injury with increased spacing between injured tubules due to interstitial fibrosis (Masson-Trichrome-stain, original magnification 100x, scale bar = 100 μm). (c) Unremarkable glomerulus (Periodic acid-Schiff reaction, original magnification 400x, scale bar = 20 μm). (d) Focal segmental vacuoles along the glomerular capillary loops consistent with intramembranous immune deposits (arrows, Jones methenamine Silver stain, original magnification 600x, scale bar = 20 μm). (e) Electron photomicrograph showing subepithelial and intramembranous electron-dense immune-type deposits with podocyte foot process effacement (unstained section original magnification 12000x, scale bar = 5 μm). (f) Electron photomicrograph displaying large TBM deposits (unstained section original magnification 12000x).