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. 1998 Sep;66(9):4244–4253. doi: 10.1128/iai.66.9.4244-4253.1998

TABLE 2.

Plasmids used in this study

Plasmid Description Purpose Antibiotic resistance Reference or source
pBluescript II KS High-copy-number cloning vector Initial subcloning Apr Stratagene
pBluescript II KS-Km HindIII/SmaI-digested wild-type Tn5 treated with the Klenow fragment and ligated to EcoRV-digested pBluescript II KS Source of aphA gene Apr Kmr This study
pGP704 oriR6K mobRP4 Suicide vector Apr 37
pGP704Km aphA gene inserted into the bla gene of pGP704 Suicide vector Kmr This study
pACYC184 Low-copy-number cloning vector Complementation Tcr Cmr 7
pUC18CML High-copy-number cloning vector Source of cat gene Apr Cmr 51
pBR322 Low-copy-number cloning vector Complementation Tcr
pRAB2401 Subclone of O75 rfb gene cluster Subcloning of rfb genes Apr 4
pSMB102 Intramolecular ligation of pRAB2401 cut with PstI Cloning of rfbD gene Apr This study
pSMB103 cat gene (SmaI/HindII) inserted into SnaBI of pSMB102 Mutation of rfbD gene Apr Cmr This study
pSMB104 EcoRV fragment of pSMB103 ligated to pGP704Km Subcloning into suicide vector for conjugation Kmr Cmr This study
pSMB105 Intramolecular ligation of pRAB2401 cut with ClaI Cloning of rfbKM genes Apr This study
pSMB106 6.5-kb ClaI/KpnI fragment of pSMB105 inserted into pBluescript II KS Subcloning of rfbKM genes Apr This study
pSMB107 Deletion of 1.1-kb NruI fragment from rfbKM and insertion of cat gene (SmaI/HindII) Mutation of rfbKM genes Apr Cmr This study
pSMB108 EcoRV/KpnI fragment of pSMB107 ligated to pGP704 Subcloning into suicide vector for conjugation Apr Cmr This study
pSMB109 MunI fragment of pSMB106 ligated to pBR322 cut with EcoRI/ScaI Cloning of rfbKM genes for complementation Tcr This study
pSMB110 ugd PCR product (EcoRV/BamHI) ligated to pBluescript II KS Cloning of sequence upstream of rol gene Apr This study
pSMB111 his PCR product (BamHI/XbaI) ligated to pSMB110 Cloning of upstream and downstream sequences of rol gene Apr This study
pSMB112 Insertion of cat gene (BamHI ends) into BamHI site of pSMB111 cat gene inserted between ugd and his Apr Cmr This study
pSMB114 EcoRV/SalI fragment of pSMB112 ligated to pGP704 Subcloning into suicide vector for conjugation Apr Cmr This study
pGH1610 galF rfbBDA04 from pGH161 (20) cut with PstI/HpaI and ligated to pBR322 cut with PstI/ScaI Cloning of rfbD gene for complementation Tcr This study
pRAB10 rol gene in pACYC184 Subcloning of rol gene for complementation Tcr 3
pSMB250 kfiCD PCR product (SalI ends) ligated to pBluescript II KS Cloning of kfiCD genes Apr This study
pSMB251-Cm Insertion of cat gene (SmaI/HindII) into NdeI-filled ends of pSMB250 Mutation of kfiC gene Apr Cmr This study
pSMB251-Km Insertion of aphA gene (filled ends) into NdeI-filled ends of pSMB250 Mutation of kfiC gene Apr Kmr This study
pSMB252-Cm SalI fragment of pSMB251-Cm ligated to pGP704 Subcloning into suicide vector for conjugation Apr Cmr This study
pSMB252-Km SalI fragment of pSMB251-Km ligated to pGP704 Subcloning into suicide vector for conjugation Apr Kmr This study