Table 6.

Results of evaluation tests of microcapsule formulations studied in stage 4.

Evaluation test	Formulation
	F10	F4	F11	F12	F13	F14	F15	F16
Polymer viscosity grade	Ethylcellulose N 100				Ethocel St 20
Drug Polymer ratio	4:1	3:1	2:1	1:1	4:1	3:1	2:1	1:1
Water content (%)	1.727 ± 0.211	1.120 ± 0.110	1.093 ± 0.131	1.113 ± 0.154	1.650 ± 0.131	1.110 ± 0.082	1.190 ± 0.111	1.173 ± 0.121
Flowability	Excellent	Excellent	Excellent	Excellent	Excellent	Excellent	Excellent	Excellent
Bulk density (g/cm3	0.277 ± 0.001	0.293 ± 0.003	0.332 ± 0.003	0.399 ± 0.003	0.274 ± 0.001	0.298 ± 0.004	0.333 ± 0.005	0.398 ± 0.004
Tapped density (g/cm3)	0.294 ± 0.002	0.311 ± 0.002	0.363 ± 0.003	0.439 ± 0.003	0.299 ± 0.003	0.313 ± 0.003	0.359 ± 0.004	0.441 ± 0.004
Angle of repose	28.423 ± 0.855	27.447 ± 0.604	27.713 ± 0.596	27.036 ± 1.027	28.313 ± 0.908	26.323 ± 0.947	26.337 ± 0.530	27.370 ± 0.771
Carr's index	5.911 ± 0.340	5.632 ± 0.298	8.465 ± 0.349	9.269 ± 1.066	8.223 ± 0.975	4.863 ± 0.356	7.177 ± 0.297	9.729 ± 0.214
Hausner ratio	1.063 ± 0.004	1.060 ± 0.003	1.092 ± 0.004	1.102 ±0.013	1.090 ± 0.012	1.051 ± 0.004	1.077 ± 0.003	1.108 ± 0.003
Encapsulation Efficiency (%)	96.327 ± 0.763	97.107 ± 0.994	98.717 ± 0.880	101.060 ± 1.091	97.647 ± 0.869	98.323 ± 0.854	99.240 ± 0.404	101.220 ± 1.484
Production Yield (%) (pooled)	96.34	97.27	95.66	93.15	97.03	96.89	96.93	94.76

Results represent the average of 3 recorded reading for each test.