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. 2024 Feb 7;24:58. doi: 10.1186/s12886-024-03321-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — The prototype software to automatically measure radii of arcs on retinal pigment epithelium (RPE) segmentation line on OCT images. (A) The machine software automatically detects the RPE segmentation line (green line). (B) Given that the raw OCT images were elongated to twice the size in the vertical dimension in the machine software, the horizontal to vertical pixel ratio was corrected to 1:1. The region of interest was defined by excluding 100 pixels in the horizontal dimension on both sides of the image (Yellow box). The arc at the pixel (a) was made by connecting two pixels (b and c) apart by 1.4 mm [100 pixels apart from the pixel (a)] on RPE segmentation line. (C) The radius of arc was calculated at every pixel on the RPE segmentation line in the region of interest and they were presented as the graph (red line). Among graphs of the radii of arc (red line), the shortest radius was named ‘r’ (mm) (Fig. 1C). The average ‘r’ of the 12 radial OCT scans was designated as ‘R’ (mm)