Table 3.
Clinical characteristics and outcome of patients with postoperative AE-ILD
| Gender /Age |
Smoking indexa/Quitting time | Comorbidity | PFT FEV1/MVV/DLCO (% pred) |
Type and history of ILD | Image feature and range of ILD | Pathology and TNM stage | Surgery | Operation time (min) |
Intraoperative blood loss (ml) | Onset of AE-ILD | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M/74 | 30/180mo | None | 80/84/53 | IPF/3mo | UIP/whole lung field | SCLC/III-a | L + SLND/VATS | 105 | 350 | POD 2 | Glucocorticoid /IMV | Died, POD 15 |
| M/73 | 50/36mo | COPD, CHD | 63.6/48.4/57.4 | IPF/36mo | UIP/whole lung field | SCC/Ia2 | W + SLND/VATS | 75 | 30 | POD 52 | NIV | Improve |
| M/76 | 75/0.5mo | COPD, CHD, AF, renal carcinoma | 92.8/93.4/64.9 | IPF/36mo | UIP/bilateral subpleural area | SCLC/Ia1 | W + SLND /VATS | 60 | 20 | POD 5 | Glucocorticoid | Improve |
| M/60 | 150/1mo | CHD, DM | 69/86/67 | IPF/240mo | UIP/bilateral subpleural area | SCLC/IIb | L + SLND /VATS | 160 | 200 | POD 3 | Glucocorticoid /NIV | Improve |
| M/74 | 50/1mo | HTN, SS, glomerular nephritis | 88/134/66 | CTD-ILD/48mo | Non-UIP/bilateral subpleural area | SCLC/IIIa | L + SLND /VATS | 230 | 600 | POD 3 | Glucocorticoid /IMV | Died, POD 38 |
| F/73 | non-smoker | HTN, SS | 60/92/64 | CTD-ILD/48mo | Non-UIP/bilateral subpleural area | IP | L/VATS | 160 | 600 | POD 3 | Glucocorticoid /NIV | Died, POD 13 |
| M/70 | non-smoker | CHD, DM | 107.4/89/61.6 | IPF/unknown |
UIP/bilateral subpleural area |
IP | S + W/VATS | 100 | 50 | POD 30 | Glucocorticoid /NIV | Died, POD 60 |
Note: a: package-years
Abbreviation: AE-ILD: acute exacerbation of interstitial lung disease; AF: atrial fibrillation; CHD: coronary heart disease; COPD: chronic obstructive pulmonary disease; CTD-ILD: Connective tissue diseases related interstitial lung disease; DLCO: diffusing capacity of carbon monoxide; DM, diabetes mellitus; F: female; FEV1: forced expiratory volume in 1 s; HTN, hypertension; ILD: interstitial lung disease; IMV: invasive mechanical ventilation; IP: Inflammatory pseudotumor; IPF: idiopathic pulmonary fibrosis; L: lobectomy; M: male; min: minute; ml: milliliter; mo: month; MVV: maximal voluntary ventilation; NIV: Non-invasive ventilation; PFT: pulmonary function test; POD: postoperative day; S: segmentectomy; SCC: Squamous cell carcinoma; SCLC: Small cell carcinoma; SLND: systematic lymph node dissection; SS: Sjogren Syndrome; UIP: usual interstitial pneumonitis; VATS: video-assisted thoracoscopic surgery; W: wedge resection;