Table 1.
Spirometry (n = 200), DLCO (n = 194) and SPB (n = 194) values in patients with post COVID syndrome
| CP disease + (n 55) | CP disease − (n 143) | CT > 7.2% (n 51) | CT < = 7.2% (n 99) | peak VO2 < 80% (n 97) | peak VO2 > 80% (n 96) | VE/VCO2 > 120% (n 67) | VE/VCO2 < 120% (n 126) | |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 53.8 ± 13.1 | 63.1 ± 16.1* | 61.6 ± 13.2 | 54.1 ± 14.9* | 53.2 ± 13.1 | 58.0 ± 14.8# | 56.1 ± 16.0 | 54.9 ± 12.8 |
| Gender (males) | 37 (67%) | 73 (51%) | 29 (57%) | 52 (53%) | 62 (64%) | 37 (36%) | 37 (55%) | 73 (58%) |
| BMI (kg/m2) | 25.5 ± 3.8 | 25.9 ± 4.2 | 27.3 ± 3.9 | 25.1 ± 3.8* | 26.1 ± 4.3 | 25.5 ± 3.6 | 26.3 ± 4.7 | 25.6 ± 3.6 |
| SPB (AU) | 84.0 [50.0–124.3] | 66.1 [44.0–90.7]* | 71.1 [52.5–114.2] | 66.6 [47.7–88.4] | 72.3 [48.5–110.6] | 64.7 [43.6–84.6]# | 69.2 [49.9–108.0] | 67.0 [44.9–92.4] |
| FVC (%) | 94 ± 19 | 101 ± 16* | 93 ± 17 | 103 ± 17* | 96 ± 17 | 104 ± 15* | 97 ± 18 | 102 ± 16# |
| FEV1(%) | 93 ± 20 | 101 ± 16* | 95 ± 17 | 101 ± 16# | 97 ± 17 | 104 ± 16* | 97 ± 18 | 102 ± 15 |
| FEV1/FVC | 86.7 ± 15.9 | 86.2 ± 13.0 | 83.6 ± 14.5 | 88.6 ± 14.4§ | 85.2 ± 14.2 | 88.7 ± 13.1 | 85.2 ± 14. 8 | 87.7 ± 13.1 |
| DLCO (mL/min/mmHg) | 21.2 ± 7.2 | 22.3 ± 6.6 | 19. 8 ± 5.9 | 23.0 ± 6.7* | 21.9 ± 7.2 | 22.9 ± 6.0 | 20.8 ± 6.7 | 23.3 ± 6.5# |
| DLCO (%) | 80 ± 20 | 82 ± 19 | 77 ± 16 | 85 ± 20* | 79 ± 21 | 86 ± 15# | 77 ± 18 | 85 ± 18* |
| DLNO (mL/min/mmHg) | 91.3 ± 32.9 | 95.2 ± 28.2 | 82.1 ± 26.5 | 99.7 ± 28.6* | 93.3 ± 29.5 | 98.4 ± 28.0 | 91.2 ± 27.9 | 99.3 ± 28.1 |
| DM (mL/min/mmHg) | 45.5 ± 17.1 | 47.8 ± 13.7 | 41.5 ± 13.4 | 50.4 ± 14.3* | 46.4 ± 15.4 | 49.8 ± 13.2 | 45.6 ± 15.0 | 49.5 ± 14.0 |
| DM (%) | 101 ± 23 | 107 ± 22 | 95 ± 20 | 113 ± 23* | 102 ± 24 | 112 ± 20* | 102 ± 22 | 110 ± 22# |
| Vcap (mL) | 57 ± 18 | 60 ± 17 | 54 ± 17 | 62 ± 15* | 58 ± 18 | 62 ± 15# | 56 ± 18 | 62 ± 15# |
| Vcap (%) | 82 ± 23 | 86 ± 22 | 81 ± 21 | 89 ± 22§ | 82 ± 23 | 88 ± 19 | 80 ± 22 | 88 ± 20# |
| VA (L) | 5.2 [4.4–5.8] | 5.2 [4.5–5.9] | 5.0 [4.1–5.6] | 5.3 [4.4–6.1]@ | 5.2 [4.5–6.2] | 5.3 [4.5–5.8] | 5.0 [4.3–5.8] | 5.4 [4.6–6.2] |
SPB: surfactant binding protein; AU: arbitrary unit; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lungs for carbon monoxide (data corrected for hemoglobin); DLNO: diffusing capacity of the lungs for nitric oxide; DM: membrane diffusion; Vcap: capillary volume; VA: alveolar volume; CP disease: history of cardiopulmonary diseases; CT: thoracic computer tomography; peak VO2: peak oxygen intake; VE/VCO2: minute ventilation/carbon dioxide production relationship. *p < 0.01; #p < 0.05; §p = 0.05; @p = 0.06