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. 2023 Oct 28;38(1):56–67. doi: 10.1177/02698811231196877

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Experience sampling of subjective effects induced by continuous infusions of placebo and different doses of DMT. The bolus IV injection was administered at time 0. The constant-rate infusion started at min 1 and was maintained until minute 30. (a) Peak effects of DMT were successfully extended via continuous infusion. A significant dose-response relationship for Intensity was found for minutes 1–40 (assessed using a 0–10 scale with 0 = ‘no effects’ and 10 = ‘most intense effects imaginable’). (b) Anxiety ratings were given on a scale from 0 to 10, with 0 = ‘no anxiety’ and 10 = ‘most intense anxiety imaginable’. The data are expressed as the mean ± SEM.