Table 2. Area per Lipid in the Membrane of the Liposomes and the Surface Charge Density, Obtained from the SAXS Analysisa.
| membrane | POPC | POPC/POPS 95/5 | POPC/POPS 90/10 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| fE [%] | 0b | 0.5 | 0 | 0.5 | 0 | 0.5 | ||||||
| leaflet | 1, 2 | 1 | 2 | av | 1, 2 | 1 | 2 | av | 1, 2 | 1 | 2 | av |
| Â [Å2] | 64.8 | 80.0 | 44.6 | 62.3 | 63.7 | 73.7 | 52.0 | 62.8 | 64.3 | 72.0 | 55.8 | 63.9 |
| ρ 10–3[e/Å2] | 0 | 0 | 0 | 0 | 0.78 | 0.68 | 0.96 | 0.80 | 1.56 | 1.39 | 1.79 | 1.56 |
| membrane | DPPC | DPPC/DPPS 95/5 | DPPC/DPPS 90/10 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| fE [%] | 0b | 0.5 | 0 | 0.5 | 0 | 0.5 | ||||||
| leaflet | 1, 2 | 1 | 2 | av | 1, 2 | 1 | 2 | av | 1, 2 | 1 | 2 | av |
| Â [Å2] | 45.5 | 47.6 | 41.7 | 44.6 | 45.1 | 47.5 | 41.7 | 44.6 | 44.3 | 46.7 | 42.0 | 44.3 |
| ρ 10–3[e/Å2] | 0 | 0 | 0 | 0 | 1.12 | 1.14 | 1.15 | 1.14 | 2.25 | 2.36 | 2.36 | 2.36 |
The looser and tighter packed leaflets of the asymmetric membranes are indexed as 1 and 2, respectively. The values averaged over two leaflets are also entered.
Own data published elsewhere.28