Table 3.
Baseline scores of different schizophrenia symptoms in patients with different genotypes.
| Total | POS | DIS | ANX | HOS | AAA | DOE | DEP | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | Mean | p (corrected p) | ||
| rs53576 | AA | 89.58 | 0.067 (1.000) | 17.86 | 0.240 (1.000) | 20.37 | 0.240 (1.000) | 4.46 | 0.517 (1.000) | 12.93 | 0.279 (1.000) | 10.08 | 0.602 (1.000) | 11.72 | 0.456 (1.000) | 4.65 | 0.602 (1.000) |
| AG | 88.76 | 17.67 | 20.17 | 4.44 | 12.72 | 10.01 | 11.77 | 4.65 | |||||||||
| GG | 91.05 | 18.03 | 20.68 | 4.61 | 13.15 | 10.23 | 12.05 | 4.77 | |||||||||
| rs11706648 | AA | 89.71 | 0.519 (1.000) | 17.75 | 0.541 (1.000) | 20.46 | 0.287 (1.000) | 4.50 | 0.612 (1.000) | 12.91 | 0.434 (1.000) | 10.14 | 0.258 (1.000) | 11.88 | 0.357 (1.000) | 4.68 | 0.827 (1.000) |
| AC | 89.08 | 17.80 | 20.16 | 4.42 | 12.88 | 9.94 | 11.65 | 4.63 | |||||||||
| CC | 88.86 | 18.06 | 20.20 | 4.53 | 12.47 | 10.23 | 11.67 | 4.66 | |||||||||
| rs2254298 | GG | 89.18 | 0.490 (1.000) | 17.83 | 0.857 (1.000) | 20.22 | 0.349 (1.000) | 4.47 | 0.978 (1.000) | 12.80 | 0.525 (1.000) | 10.05 | 0.427 (1.000) | 11.77 | 0.894 (1.000) | 4.65 | 0.717 (1.000) |
| GA | 89.34 | 17.78 | 20.29 | 4.47 | 12.96 | 9.99 | 11.71 | 4.65 | |||||||||
| AA | 90.49 | 17.92 | 20.72 | 4.50 | 13.10 | 10.31 | 11.82 | 4.76 | |||||||||
| rs2268490 | CC | 89.74 | 0.068 (1.000) | 17.91 | 0.005* (0.266) | 20.29 | 0.550 (1.000) | 4.49 | 0.416 (1.000) | 12.88 | 0.983 (1.000) | 10.16 | 0.014* (0.794) | 11.83 | 0.775 (1.000) | 4.63 | 0.706 (1.000) |
| CT | 88.75 | 17.61 | 20.19 | 4.40 | 12.91 | 9.88 | 11.72 | 4.65 | |||||||||
| TT | 90.63 | 18.26 | 20.48 | 4.55 | 12.92 | 10.40 | 11.86 | 4.73 | |||||||||
| rs1042778 | GG | 89.36 | 0.815 (1.000) | 17.79 | 0.808 (1.000) | 20.33 | 0.702 (1.000) | 4.47 | 0.820 (1.000) | 12.84 | 0.490 (1.000) | 10.06 | 0.848 (1.000) | 11.77 | 0.904 (1.000) | 4.66 | 0.828 (1.000) |
| GT/TT | 89.55 | 17.84 | 20.24 | 4.49 | 13.00 | 10.09 | 11.79 | 4.68 | |||||||||
| rs237899 | GG | 89.00 | 0.013* (0.741) | 17.77 | 0.523 (1.000) | 20.25 | 0.166 (1.000) | 4.45 | 0.447 (1.000) | 12.76 | 0.035* (1.000) | 10.01 | 0.164 (1.000) | 11.75 | 0.555 (1.000) | 4.64 | 0.373 (1.000) |
| GA/AA | 90.76 | 17.88 | 20.55 | 4.53 | 13.21 | 10.23 | 11.86 | 4.72 | |||||||||
| rs13316193 | TT | 89.58 | 0.243 (1.000) | 17.85 | 0.226 (1.000) | 20.41 | 0.134 (1.000) | 4.53 | 0.044* (1.000) | 12.83 | 0.493 (1.000) | 10.05 | 0.836 (1.000) | 11.76 | 0.982 (1.000) | 4.68 | 0.326 (1.000) |
| TC/CC | 88.83 | 17.66 | 20.10 | 4.34 | 12.96 | 10.02 | 11.77 | 4.60 | |||||||||
POS positive, DIS disorganized, NAA negative symptoms apathy/avolition, NDE negative symptoms deficit of expression, HOS hostility, ANX anxiety, DEP depression.
*p < 0.05.