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. 2024 Jan 6;10(1):7. doi: 10.1038/s41537-023-00413-5

Table 4.

After 6-week treatment with antipsychotics, percentage changes of different schizophrenia symptoms in patients with different genotypes.

POS DIS ANX HOS AAA DOE DEP
Mean p (corrected p) Mean p (corrected p) Mean p (corrected p) Mean p (corrected p) Mean p (corrected p) Mean p (corrected p) Mean p (corrected p)
rs53576 AA 60.91 0.458 (1.000) 41.01 0.230 (1.000) 65.05 0.841 (1.000) 75.92 0.355 (1.000) 46.83 0.093 (1.000) 45.65 0.366 (1.000) 53.02 0.195 (1.000)
AG 59.25 39.41 63.74 74.98 43.43 43.46 49.72
GG 60.30 41.99 64.37 78.12 45.89 43.35 58.34
rs11706648 AA 59.86 0.603 (1.000) 40.74 0.432 (1.000) 63.69 0.752 (1.000) 75.62 0.917 (1.000) 45.73 0.841 (1.000) 43.66 0.488 (1.000) 51.20 0.270 (1.000)
AC 60.80 40.53 65.16 76.05 44.82 45.61 51.96
CC 58.60 38.02 65.78 75.17 45.28 44.13 60.30
rs2254298 GG 60.33 0.065 (1.000) 39.63 0.278 (1.000) 64.44 0.901 (1.000) 75.78 0.886 (1.000) 44.25 0.024* (1.000) 43.53 0.112 (1.000) 52.96 0.653 (1.000)
GA 58.78 40.66 64.75 75.40 44.88 44.13 50.31
AA 64.16 42.65 62.92 76.53 51.80 49.63 53.39
rs2268490 CC 60.44 0.336 (1.000) 39.44 0.095 (1.000) 66.20 0.581 (1.000) 75.70 0.652 (1.000) 43.85 0.039* (1.000) 44.79 0.146 (1.000) 52.72 0.671 (1.000)
CT 59.40 40.30 63.47 75.48 44.65 43.85 52.84
TT 61.99 42.91 65.27 77.14 49.31 48.13 56.12
rs1042778 GG 59.87 0.291 (1.000) 40.13 0.166 (1.000) 64.42 0.955 (1.000) 75.38 0.166 (1.000) 45.23 0.766 (1.000) 44.51 0.952 (1.000) 51.75 0.495 (1.000)
GT/TT 61.70 42.20 64.58 77.82 45.84 44.38 54.42
rs237899 GG 60.24 0.790 (1.000) 40.39 0.829 (1.000) 64.77 0.542 (1.000) 75.53 0.481 (1.000) 45.45 0.749 (1.000) 44.55 0.893 (1.000) 51.94 0.756 (1.000)
GA/AA 59.84 40.67 63.20 76.62 44.87 44.30 53.03
rs13316193 TT 60.18 0.752 (1.000) 40.85 0.153 (1.000) 64.11 0.582 (1.000) 75.59 0.847 (1.000) 45.95 0.120 (1.000) 44.40 0.870 (1.000) 50.67 0.132 (1.000)
TC/CC 59.75 39.17 65.40 75.86 43.42 44.11 55.55

*p < 0.05.