Table 3.

Comparisons of the prognostic performance of age SI, age MSI versus TIMI risk score and GRACE score.

Endpoints	AUC difference (95% CI)	p for C-statistic	NRI	p for NRI	IDI	p for IDI
Post-discharge mortality within 30 days
Age SI vs. TIMI risk score	−0.026 (–0.080, 0.028)	.344	−0.001 (–0.010, 0.009)	.898	−0.292 (–0.596, 0.012)	.060
Age MSI vs. TIMI risk score	−0.024 (–0.074, 0.026)	.352	0.002 (–0.009, 0.013)	.678	−0.438 (–0.734, –0.142)	.005
Age SI vs. GRACE score	0.024 (–0.023, 0.071)	.317	0.0002 (–0.008, 0.009)	.961	−0.089 (–0.392, 0.214)	.566
Age MSI vs. GRACE score	0.026 (–0.011, 0.063)	.161	0.003 (–0.007, 0.013)	.530	−0.139 (–0.443, 0.165)	.371
Post-discharge mortality from 30 days to 1 year
Age SI vs. TIMI risk score	−0.014 (–0.075, 0.048)	.670	−0.002 (–0.021, 0.017)	.836	−0.380 (–0.618, –0.143)	.002
Age MSI vs. TIMI risk score	−0.004 (–0.061, 0.053)	.896	−0.005 (–0.020, 0.011)	.550	−0.309 (–0.548, –0.070)	.012
Age SI vs. GRACE score	−0.009 (–0.057, 0.039)	.722	−0.004 (–0.018, 0.011)	.627	−0.372 (–0.611, –0.133)	.002
Age MSI vs. GRACE score	0.001 (–0.046, 0.047)	.968	−0.006 (–0.018, 0.005)	.279	−0.367 (–0.606, –0.128)	.003

AUC: area under the curve; CI: confidence intervals; NRI: net reclassification improvement; IDI: integrated discrimination improvement; SI: shock index; MSI: modified shock index; TIMI: thrombolysis in myocardial infarction; GRACE: Global Registry of Acute Coronary Events.