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Overall immune characteristics of syngeneic murine GBM models
| GL261 | SB28 | CT-2A | SMA-560 | |
|---|---|---|---|---|
| Overall immunogenicity | High | Low | Low | Moderate |
| MHC class I | High | None | Low | Low |
| MHC class II | Low/none | None | Low | None |
| PD-L1 | Present | Present | Present | Present |
| PD-L2 | None | Unknown | Unknown | Unknown |
| Mutational load | Very high | Low | Moderate | High |
PD-L2 = programmed death-ligand 2.
