Figure 1. Plasma Levels of Androgenic and Nonandrogenic Steroid Hormones during Treatment with ODM-208 5 mg Twice a Day in Patients in Phase 2.
In all five panels, the y axis is a log scale. Most values above the lower limit of quantification (LLoQ) after day 1 were detected in patients in whom ODM-208 administration had been interrupted. Samples below the LLoQ were superimposed as half the LLoQ. Testosterone (Panel A). Androstenedione (Panel B). Dehydroepiandrosterone sulfate (Panel C). Aldosterone (Panel D). Cortisol (Panel E). D denotes day; and W, week.