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. 2019 May 7;34(5):302–307. doi: 10.1177/1533317519848237

Table 2.

Cytochrome P450 (CYP) Genotypes and Adverse Side Effects.a

Side-Effect
0 ≥1 P Value
(A)
CYP2D6 *10
 Carrier 47 (77%) 14 (23%) .009
 Noncarrier 9 (45%) 11 (55%)
(B)
Genotype
 CYP2D6*10 noncarrier & CYP3A4*1G carrier 2 (25.0%) 6 (75.0%) .013
 Others 45 (72.6%) 17 (27.4%)

a(A) Association between CYP2D6 *10 and adverse side effect in patients prescribed with donepezil or galantamine. (B) Association between CYP2D6 *10 and CYP*3A4 and the occurrence of side effect in patients prescribed with donepezil or galantamine.