Table 2.

Neuropsychiatric Inventory Frequency Per Symptom in Patients With EOAD and LOAD.

Domain	Frequency, n (%)										P Value
	EOAD, n = 35					LOAD, n = 35
	Not present	Occasionally	Often	Frequently	Very frequently	Not present	Occasionally	Often	Frequently	Very frequently
Delusions	33 (94.3)	0	1 (2.9)	1 (2.9)	0	31 (88.6)	1 (2.9)	1 (2.9)	1 (2.9)	1 (2.9)	.397
Hallucinations	35 (100)	0	0	0	0	33 (94.3)	1 (2.9)	0	1 (2.9)	0	.154
Agitation/aggression	26 (74.3)	3 (8.6)	4 (11.4)	1 (2.9)	1 (2.9)	22 (62.9)	5 (14.3)	5 (14.3)	1 (2.9)	2 (5.7)	.327
Depression/dysphoria	21 (60)	3 (8.6)	6 (17.1)	2 (5.7)	3 (8.6)	17 (48.6)	3 (8.6)	5 (14.3)	7 (20)	3 (8.6)	.268
Anxiety	18 (51.4)	0	4 (11.4)	9 (25.7)	4 (11.4)	16 (45.7)	1 (2.9)	10 (28.6)	6 (17.1)	2 (5.7)	.748
Elation/euphoria	34 (97.1)	0	1 (2.9)	0	0	34 (97.1)	0	0	0	1 (2.9)	.984
Apathy/indifference	14 (40)	3 (8.6)	4 (11.4)	4 (11.4)	10 (28.6)	18 (51.4)	0	4 (11.4)	7 (20)	6 (17.1)	.386
Disinhibition	31 (88.6)	1 (2.9)	1 (2.9)	2 (5.7)	0	31 (88.6)	0	1 (2.9)	0	3 (8.6)	.907
Irritability/lability	11 (31.4)	4 (11.4)	12 (32.3)	7 (20)	1 (2.9)	15 (42.9)	1 (2.9)	7 (20)	8 (22.9)	4 (11.4)	.883
Aberrant motor behavior	26 (74.3)	2 (5.7)	0	3 (8.6)	4 (11.4)	29 (82.9)	0	3 (8.6)	2 (5.7)	1 (2.9)	.330
Nighttime behaviors	24 (68.6)	2 (5.7)	4 (11.4)	2 (5.7)	3 (8.6)	26 (74.3)	0	3 (8.6)	5 (14.3)	1 (2.9)	.679
Appetite/eating	23 (65.7)	2 (5.7)	4 (11.4)	1 (2.9)	5 (14.3)	27 (77.1)	1 (2.9)	5 (14.3)	1 (2.9)	1 (2.9)	.232
NPI total frequency, mean (SD)	9.2 (5.2)					9.1 (6.0)					.966

Abbreviations: EOAD, early onset Alzheimer’s disease; LOAD, late onset Alzheimer’s disease; NPI, Neuropsychiatric Inventory; SD, standard deviation.