Table 5.
Issues to Consider in the Diagnosis of PD-MCI. 60
| No. | Issues |
|---|---|
| 1 | Availability of subjective and objective data from sources including the patient, informant, clinician, and neuropsychological tests |
| 2 | Initial versus serial evaluations |
| 3 | Clinical information |
| a) Presence of cognitive (not only memory) complaints and by whom (patient, informant, clinician) | |
| b) Assessment of functioning in activities of daily living and differentiating cognitive effects from motor impairment | |
| c) Presence of comorbid nonmotor features: depression, anxiety, apathy, psychosis, fatigue, sleep disturbances, and their impact on cognition and during neuropsychological tests | |
| 4 | Neuropsychological testing |
| a) Selection of specific cognitive tests or screening instruments, use of normative data, and cutoff scores | |
| b) Motor state (“on” versus “off”) during neuropsychological testing | |
| c) Motor demands of some neuropsychological tests | |
| d) Effect of mood disorders, psychosis, fatigue, and daytime sleepiness on neuropsychological test performance |
Abbreviation: PD-MCI, mild cognitive impairment in Parkinson disease.