Table 4.

Neuropsychological Assessment Recommendations in AD Dementia Guidelines.

.	Level of Evidence	Grade of Recommendation
“Fomal neuropsychological testing should form part of the assessment in cases of mild or questionable dementia” 18	Expert consensus	No strength
“Neuropsychological testing should be used in the diagnosis of dementia, especially in patients where dementia is not clinically obvious” 19	1++, 2++	B
“The diagnosis and differential diagnosis of dementia is currently a clinically integrative one. Neuropsychological testing alone cannot be used for this purpose and should be used selectively in clinical settings. Neuropsychological testing may aid in: addressing the distinction between normal aging, mild cognitive impairment or cognitive impairment without dementia, and early dementia; addressing the risk of progression from mild cognitive impairment or cognitive impairment without dementia to dementia or Alzheimer dementia; determining the differential diagnosis of dementia and other syndromes of cognitive impairment.” 25	2	B
“When the diagnosis of dementia is inconclusive, then neuropsychological tests will be required” 36	III	C
“We recommend performed a detailed neuropsychological evaluation by specific tests when there are discrepancies between the clinical impression and screening tests, diagnostic concerns or when the complaints are of short duration or limited to a single cognitive domain” 34	4	D
“Quantitative neuropsychological testing should be made in patients with questionable or very early Alzheimer Dementia” 30 “The assessment of cognitive functions should include a general cognitive measure and more detailed testing of the main cognitive domains, and in particular an assessment of delay recall” 30	III, I	B, A

Abbreviation: AD, Alzheimer’s disease.