Table 3.
Meta-Analysis of ApoE Alleles and Risk of AD in the Indian Population.
| Alleles | Random Effects Model, OR (95% CI) | Fixed Effects Model, OR (95% CI) | Heterogeneity Test, P Value | Degree of Heterogeneity, I 2 in % | ||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | |
| ApoE ∊2 | 0.70 (0.38-1.30) | 0.69 (0.37-1.31) | 0.84 (0.56-1.24) | 0.73 (0.50-1.07) | .09 | .08 | 44.51 | 46.72 |
| ApoE ∊3 | 0.29 (0.17-0.50) | 0.29 (0.17-0.50) | 0.29 (0.17-0.50) | 0.26 (0.15-0.44) | .48 | .46 | 0.00 | 0.00 |
| ApoE ∊4 | 5.87 (3.46-9.96) | 5.90 (3.44-10.13) | 5.02 (3.69-6.82) | 5.65 (4.21-7.59) | .02 | .02 | 58.98 | 60.53 |
Abbreviations: AD, Alzheimer’s disease; ApoE, apolipoprotein E; OR, odds ratio; CI, confidence interval.