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. 1998 Sep;66(9):4355–4366. doi: 10.1128/iai.66.9.4355-4366.1998

TABLE 1.

Known GSL receptors for Stx and Shiga-like toxinsa

GSL family Name (symbol) GSL structureb
gala Galabiosylceramide Galα1→4Galβ1→1′Cer
globo Globotriaosylceramide (Gb3, CTH, CD77, Pk) Galα1→4Galβ1→4Glcβ1→1′Cer
neolacto IV4-α-Galactosylneolactotetraglycosylceramide (P1) Galα1→4Galβ1→4GlcNAcβ1→3Galβ1→4Glcβ1→1′Cer
globoc Globotetraosylceramide (Gb4,P) GalNAcβ1→3Galα1→4Galβ1→4Glcβ1→1′Cer
a

GSL classification, trivial names, and structures as recommended by the International Union of Pure and Applied Chemistry-International Union of Biology Commission on Biochemical Nomenclature (47). 

b

Underlined oligosaccharides represent the critical terminal Galα1-4Gal disaccharide required for Stx, Stx1, and Stx2 recognition and binding. 

c

Receptor for Stx2e.