TABLE 4.

ELISA and complement-mediated bactericidal titers to whole bacterial cells of multiple isolates of M. catarrhalis elicited by purified UspA1 and purified UspA2

Isolate	Whole cell ELISAa		Bactericidal titerb
	Anti-UspA1	Anti-UspA2	Anti-UspA1	Anti-UspA2
O35E	195,261	133,492	400	800
430-345	12,693	18,217	400	400
1230-359	7,873	13,772	400	400
TTA24	14,341	7,770	800	800

^aThe titer was determined for a pool of sera from 10 mice. The titer of the serum drawn before the first immunization was <50 for all isolates. 

^bBactericidal titers were determined as the inverse of the highest serum dilution killing >50% of the bacteria. The titers for the sera from mice immunized contemporaneously with CRM₁₉₇ were <100.