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. 2024 Feb 8;8(3):bvad179. doi: 10.1210/jendso/bvad179

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© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — GAD65Ab positivity correlated with competition binding to GAD65. All plasma samples from the GRADE Beta Cell Ancillary Study were re-analyzed for binding to GAD65. a, GAD65Ab indices obtained in the present analysis correlated with those reported previously [10]. The line for simple linear regression is shown together with R-value and P-value. b, GAD65Ab positivity was confirmed in a displacement assay using recombinant human GAD65 as a competitor. The cutoff for positivity (40% competition) is indicated by the dashed line. Samples that were subsequently analyzed for GAD65Ab epitopes are indicated by red dots.