Table 3.

Use the expression levels of circBRIP1, CEA, SCC, Cyfra21-1 to distinguish NSCLC patients from healthy donors

	SEN	SPN	ACCU	PPV	NPV
circBRIP1	0.83 (83/100)	0.58 (58/100)	0.71 (141/200)	0.66 (83/125)	0.77 (58/75)
CEA	0.39 (39/100)	0.94 (94/100)	0.67 (131/200)	0.87 (39/45)	0.61 (94/155)
SCC	0.28 (28/100)	0.98 (96/100)	0.62 (124/200)	0.88 (28/32)	0.57 (96/168)
Cyfra21-1	0.41 (41/100)	0.87 (87/100)	0.64 (128/200)	0.76 (41/54)	0.60 (87/146)
circBRIP1 + CEA	0.90 (90/100)	0.54 (54/100)	0.72 (144/200)	0.66 (90/136)	0.84 (54/64)
circBRIP1 + SCC	0.90 (90/100)	0.55 (55/100)	0.73 (145/200)	0.67 (90/135)	0.85 (55/65)
circBRIP1 + Cyfra21-1	0.92 (92/100)	0.51 (51/100)	0.72 (143/200)	0.65 (92/141)	0.86 (51/59)
circBRIP1 + CEA + SCC	0.92 (92/100)	0.51 (51/100)	0.72 (143/200)	0.65 (92/141)	0.86 (51/59)
circBRIP1 + CEA + Cyfra21-1	0.94 (94/100)	0.51 (51/100)	0.73 (146/200)	0.66 (94/143)	0.89 (51/57)
circBRIP1 + SCC + Cyfra21-1	0.93 (93/100)	0.47 (47/100)	0.70 (140/200)	0.64 (93/146)	0.87 (47/54)
circBRIP1 + CEA + SCC + Cyfra21-1	0.95 (95/100)	0.44 (44/100)	0.70 (139/200)	0.63 (95/151)	0.90 (44/49)