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. 2024 Feb 8;150(2):83. doi: 10.1007/s00432-023-05558-5

Table 4.

Use the expression levels of circBRIP1, CEA, SCC, Cyfra21-1 to distinguish NSCLC patients from BPD

SEN SPN ACCU PPV NPV
circBRIP1 0.56 (56/100) 0.88 (34/40) 0.65 (91/140) 0.92 (56/61) 0.44 (35/79)
CEA 0.39 (39/100) 0.70 (28/40) 0.48 (67/140) 0.76 (39/51) 0.31 (28/89)
SCC 0.28 (28/100) 0.55 (22/40) 0.36 (50/140) 0.61 (28/46) 0.23 (22/94)
Cyfra21-1 0.41 (41/100) 0.2 (8/40) 0.35 (49/140) 0.56 (41/73) 0.12 (8/67)
circBRIP1 + CEA 0.76 (76/100) 0.63 (25/40) 0.72 (101/140) 0.72 (76/106) 0.71 (25/35)
circBRIP1 + SCC 0.70 (70/100) 0.45 (18/40) 0.63 (88/140) 0.63 (70/112) 0.64 (18/28)
circBRIP1 + Cyfra21-1 0.73 (73/100) 0.20 (8/40) 0.58 (81/140) 0.59 (73/124) 0.50 (8/16)
circBRIP1 + CEA + SCC 0.80 (80/100) 0.30 (12/40) 0.66 (92/140) 0.67 (80/120) 0.60(12/20)
circBRIP1 + CEA + Cyfra21-1 0.81 (81/100) 0.23 (9/40) 0.64 (90/140) 0.72 (81/112) 0.32(9/28)
circBRIP1 + SCC + Cyfra21-1 0.77 (77/100) 0.15 (6/40) 0.59 (83/140) 0.69 (77/111) 0.21(6/29)
circBRIP1 + CEA + SCC + Cyfra21-1 0.83 (83/100) 0.15 (6/40) 0.64 (89/140) 0.71 (83/117) 0.26(6/23)