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. 2024 Jan 26;15:1223858. doi: 10.3389/fphar.2024.1223858

TABLE 3.

Characteristics of intercurrent events.

RCT OC
Number of patients 849 3340
Median (95% CI) follow-up time, months 26.5 (19.9–28.8) 35.6 (29.4–43)
Switch to subsequent therapy (any), n (%) 449 (52.9%) 1881 (56.3%)
Median (IQR) time to switch (among patients who switched), months 6.24 (4.27–9.69) 5.45 (3.12–9.43)
Number of patients who switched prior to 6 months/Number of patients who ever switched, n (%) 207/449 (46.1) 1049/1881 (55.8)

Notes: CI, confidence interval; IQR, interquartile range; OC, observational comparator; RCT, randomized clinical trial.