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Construction of predictive model for infliximab non-response. (A) Cross-validation for tuning parameter selection using LASSO regression. (B, C) ROC curves demonstrating the ability of OSM, CXCL5, and the nomogram to predict infliximab non-response. (D) Nomogram for predicting infliximab non-response in CD patients. (E, F) Differential expression of CXCL5 and OSM among controls, C1 cluster, and C2 cluster in GSE112366 (**p < 0.01 and ***p < 0.001).
