FIG. 1.

Alignment of streptococcal M5 peptides C2A and C3 with the β heavy chain of human cardiac myosin (21). Identical residues are indicated with two dots, while a conservative substitution is indicated by a single dot as determined by the FASTA alignment program (Intelligenetics, Mountain View, Calif.). The sequence identified as homologous between C2A, C3, and myosin is highly conserved (identical) between skeletal and cardiac myosin. The identical residues are located in the heavy meromyosin fragment of skeletal and cardiac myosin.