Table 2.
Direct target of Z. bungeanum polyphenols.
| Polyphenols | Target | Verified by | Publication |
|---|---|---|---|
| Rutin | HMGB1 | SPR | (112) |
| Quercetin | HMGB1 | SPR | (112) |
| PI3K1R | SPR | (113) | |
| Kaempferol | HMGB1 | SPR | (114) |
| TNF- α | SPR | (115) | |
| CASP3 PARP1 |
SPR | (116) | |
| JAK3 | IP | (117) |
*SPR, Surface plasmon resonance;
BLI, Bio-Layer Interferometry;
IP, Immunoprecipitation;
ChIP, Chromatin immunoprecipitation.