Table 3.
Completed clinical trials utilizing Z. bungeanum polyphenols.
| Compound | ID | Study phase | Dose & Administraton | Condition | Publication |
|---|---|---|---|---|---|
| Quercetin and Rutin | NCT01847521 | 2 | Quercetin 70 mg/10kg/d and Rutin 30 mg/10kg/d po |
Autism Spectrum Disorders | / |
| Rutin | NCT03437902 | 2 & 3 | 180mg po | Type 2 Diabetes Mellitus | / |
| Quercetin | NCT00913081 | 4 | 500-2000 mg po one time | Flushing | / |
| NCT01708278 | 1 | 500-2000 mg/d po | Chronic Obstructive Pulmonary Disease | (118) | |
| NCT02463357 | 4 | 1000mg/d po | Mountain Sickness | / | |
| NCT01722669 | 1 | 500mg po | Healthy | (119) | |
| Epicatechin | NCT01856868 | 1 & 2 | 100mg/day, po | Becker Muscular Dystrophy | / |
| NCT03236662 | 2 | 100mg/day, po | Becker Muscular Dystrophy | / | |
| NCT01691404 | / | 100mg/d po | Hypertension, Endothelial Dysfunction | (120–122) | |
| Naringenin | NCT01091077 | 1 | 1000mg po | HCV Infection | / |
| NCT04697355 | / | 900mg/d po | Energy Expenditure Safety Issues Glucose Metabolism |
/ | |
| Kaempferol | NCT06060691 | 1 | Topical | Female Sexual Dysfunction | / |
| Arbutin | NCT03868748 | 1 | 150-400mg/d po | Healthy Volunteers | / |
| Chlorogenic acid | NCT02245204 | 1 | Injection* | Advanced Cancer | / |
| NCT02136342 | 1 | Injection* | Advanced Cancer | / | |
| NCT02728349 | 1 | Injection* | Glioblastoma | / | |
| NCT02728349 | 1 | Injection* | Glioblastoma | / | |
| NCT03758014 | 2 & 3 | Injection* 3 mg/kg/d | Glioblastoma | / | |
| NCT02621060 | 2 | 1200 mg/d po | Impaired Glucose Tolerance | / | |
| NCT02929901 | 2 & 3 | 200mg/d po | Type 2 Diabetes Nonalcoholic Fatty Liver | (123) |