Table 1.

Psychiatric co-morbidity with ASD prevalence and clinical presentation (4).

Psychiatric Co-Morbidity	Prevalence of Co-Morbidity in Children with ASD	Clinical Presentation of Co-occurrence with ASD
Intellectual Disability	22.9%	Defined in terms of measurement tools, WISC-4 and FSIQ, however did not incorporate overall adaptive functioning and IQ scores alone cannot point to the severity level of ID. Authors noted that there is “poor testability” of subjects with comorbid ASD, which led to significant variance in results. Adaptive functioning, meanwhile, was not reported.
Attention-Deficit Hyperactivity Disorder	26.2%	Inattention, hyperactivity-impulsivity, impairments in activities of daily living, social adaptation, behavior problems
Internalizing Disorders Anxiety Disorder Depression	11.1% 2.7%	Social communication problems, sensory aversions, disruptive emotional dysregulation, inflexible adherence to routines, difficulty tolerating change.
Sleep disorder	19.7%	Heightened daytime cognitive, adaptive, and behavioral problems.
Disruptive Disorder	7%	Oppositional defiant disorder, conduct disorder, and disruptive behavior problems.
Bipolar Disorder	2%	Prevalence increased as older age groups were included in the analysis.
Obsessive-Compulsive Disorder	1.8%	Restrictive repetitive behaviors associated with ASD tend to be ego-syntonic compared to ego-dystonic nature of OCD symptoms.
Psychosis	0.6% (1.1% among adolescents)	Behavioral phenotypes of known genetic conditions such as 22q11 deletion syndrome possibly connected to greater likelihood for the identification of psychosis.