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. 2024 Jan 26;15:1330374. doi: 10.3389/fphar.2024.1330374

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Copyright © 2024 Ceccherini, Gisone, Persiani, Ippolito, Falleni, Cecchettini and Vozzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of the anti-inflammatory properties of Quercetin extract. The amount of IL-6 (A), TNF-α (B), and caspase-1 activity (C) was quantified in VSMC culture media. C: control cells (VSMC grown in medium 231); CM: VSMCs grown in the calcifying medium; CM + Q100µM: VSMCs grown in the calcifying medium supplemented with Quercetin extract at the concentration indicated. Data represent the mean of 3 independent experiments. Statistical analysis was performed with one-way ANOVA and Dunnett multiple comparison test; p-value ≤0.05 was considered significant.