Figure 11.

In vitro experiments demonstrate that the inhibition of PAK2 leads to reduced proliferation and invasion capabilities in pancreatic cancer cell lines. (A, B) Real-time fluorescence quantitative PCR was conducted on PANC-1 and Bx-Pc-3 cells (n=3, one-way ANOVA, P<0.0001). (C, D) CCK-8 cell proliferation experiments were performed on PANC-1 and Bx-Pc-3 cells (n=4, two-way ANOVA, P<0.01). (E) Comparison of migration areas after scratch assays on PANC-1 and Bx-Pc-3 cells (n=3, Welch’s test, P<0.05). ns represents no statistical significance, represents * represents P<0.05, **** represents P<0.0001.