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. 2024 Feb 8;14:3242. doi: 10.1038/s41598-024-52744-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mean tCho concentrations at 3 months separated into participants with concussion and somatic symptoms, those with concussion but without persisting somatic symptoms, and orthopedic injury (OI). Symptomatic and asymptomatic were defined at 3 months. The black lines in the boxes represent the median and the box represents the interquartile range, with the 1.5 times the interquartile range values represented by the whiskers. The asterisk indicates a significant group difference (p = 0.047) between OI and symptomatic groups.