FIGURE 5.

Keratins were significantly upregulated in UVB‐treated Livin^ΔKC mice. (A) Protein interaction analysis of UVB‐treated Livin^fl/fl and Livin^ΔKC mice. (B) A lower dose of UVB radiation (250 mJ/cm²) did not induce increases in keratin 14 and keratin 17 levels in Livin^fl/fl mice, while there were significant increases in keratin 14 and keratin 17 levels in Livin^ΔKC mice. (C) A higher dose of UVB (500 mJ/cm²) induced increases in keratin 17 and keratin 14 levels in Livin^fl/fl mice, while Livin^ΔKC mice exhibited significantly higher levels than Livin^fl/fl mice, as assessed through ELISA analysis. Data are presented as the mean ± SEM (n = 8/group) and were assessed using two‐way ANOVA. Statistical significance is denoted as * for p < 0.05 and ** for p < 0.01.