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Histologic results showing knockdown of HTRA1 downregulates GBM cell invasion and growth in vivo. (A) Representative images of HE staining showing the margins between xenografts and normal brain. Bar = 100 μm. (B, C) Representative images of immunohistochemistry detecting N‐cadherin, fibronectin, ac‐α‐tubulin and Ki‐67 in LN229‐ and GBM#P3‐shHTRA1 xenografts and the percent of expression of these four proteins. (C), Student's t‐test. *P < 0.05; **P < 0.01. Bar = 100 μm.
