Table 2.

First subjective response to opioid exposure items by cluster derived using two-step cluster analysis

	Cluster
Item	Negative response (n=127)	Low sedation (n=71)	Euphoric response (n=69)	Omnibus test P value
Sleepy	99.2%	0.0%	84.1%	<0.001
Energized	0.8	4.2	2.9	0.27
Nauseous	44.9	35.2	15.9	<0.001
Euphoric	3.9	2.8	27.5	<0.001
Sedated	56.7	23.9	52.2	<0.001
Comfortable	0.0	38.0	95.7	<0.001
Numb	20.5	5.6	20.3	0.02
Uncomfortable	24.4	22.5	0.0	<0.001
Agitated	7.9	4.2	5.8	0.59
Happy	0.4	0.7	6.7	<0.001
Drunk	13.4	12.7	7.2	0.42
Powerful	0.0	0.0	4.3	0.01

Note: Items that appeared most unique between the three clusters are in bold font.