Table 4.
Pearson correlations (r) between HOME subscales and placebo-controlled analgesic and subjective responses to morphine
Morphine Response Outcome | Home subscale | |||
---|---|---|---|---|
Cumulative opioid exposure | Euphoric response | |||
Pearson r | P value | Pearson r | P value | |
DELTA drug effect | −0.01 | 0.98 | −0.44 | 0.003 |
DELTA drug liking | −0.09 | 0.56 | 0.27 | 0.08 |
DELTA desire to take again | −0.03 | 0.85 | 0.34 | 0.02 |
Sedation factor | −0.18 | 0.21 | −0.30 | 0.04 |
Unpleasantness factor | 0.15 | 0.31 | −0.21 | 0.17 |
Euphoria factor | −0.08 | 0.59 | 0.32 | 0.03 |
MPQ-2 continuous | −0.35 | 0.02 | −0.08 | 0.59 |
MPQ-2 intermittent | −0.17 | 0.24 | 0.25 | 0.11 |
MPQ-2 neuropathic | −0.32 | 0.02 | 0.00 | 0.98 |
MPQ-2 affective | −0.24 | 0.09 | 0.06 | 0.70 |
MPQ-2 total | −0.33 | 0.02 | 0.06 | 0.69 |
Significant correlations are highlighted in bold text.
DELTA, Drug Effect, Drug Liking, and Desire to Take Again scale; HOME, History of Opioid Medication Exposure survey; MPQ-2, Short Form McGill Pain Questionnaire-2.