Figure 2.

Setting affects participants’ subjective reports of their psychedelic experiences. (a) Average increases in VAS ratings between LSD and placebo show a varied profile across experimental conditions, suggesting that setting modulates participants’ rating of their own experience. Simple and complex imagery data were not collected under the eyes-open and video conditions. (b) Effect sizes obtained from LME modeling confirm a strong effect from the drug in all items, as well as smaller and more specific effects from the stimulus. (c) Between-subjects correlation matrices between experience reports (*: p < 0.05,**: p < 0.01,***: p < 0.001).