. 2024 Feb 8;25(1):18. doi: 10.1186/s10194-024-01728-z

Table 2.

Univariable regression analysis of the variables associated with the presence of headache. Differing denominators indicate subgroup analyses

Variable	Type of analysis	Odds ratio	95% CI lower bound	95% CI upper bound	P value	FDR-adjusted P value
Female sex	Univariable	1.092	0.994	1.200	0.068
Female sex	Multivariable	1.134	1.023	1.257	0.017	0.034
Cardiovascular disorders	Univariable	0.976	0.721	1.323	0.878
Diabetes	Univariable	2.044	1.448	2.884	< 0.001
Diabetes	Multivariable	1.211	0.841	1.743	0.303	0.428
COPD	Univariable	1.777	1.037	3.045	0.036
COPD	Multivariable	1.209	0.685	2.138	0.514	0.633
Cancer	Univariable	1.489	0.845	2.623	0.168
Cancer	Multivariable	1.050	0.574	1.923	0.873	0.873
Kidney disorders	Univariable	2.915	0.858	9.905	0.086
Kidney disorders	Multivariable	1.922	0.529	6.985	0.321	0.428
Hepatic disorders	Univariable	1.212	0.38	3.869	0.745
Obesity	Univariable	1.687	0.948	3.003	0.075
Obesity	Multivariable	1.171	0.628	2.185	0.620	0.709
Smoking habit	Univariable	1.163	0.91	1.486	0.228
Vaccination	Univariable	0.973	0.771	1.226	0.814
Onset within 48 h	Univariable	1.253	1.139	1.379	< 0.001
Epidemiological contact	Univariable	1.232	1.117	1.36	< 0.001
Epidemiological contact	Multivariable	1.070	0.960	1.193	0.220	0.352
Sudden onset	Univariable	2.098	1.751	2.514	< 0.001
Sudden onset	Multivariable	1.359	1.100	1.680	0.004	0.010
Fever	Univariable	2.012	1.646	2.460	< 0.001
Fever	Multivariable	1.500	1.180	1.907	0.001	0.003
Shivering	Univariable	3.404	3.082	3.76	< 0.001
Shivering	Multivariable	1.920	1.713	2.152	< 0.001	< 0.001
Asthenia	Univariable	3.572	3.203	3.983	< 0.001
Asthenia	Multivariable	1.955	1.728	2.212	< 0.001	< 0.001
Myalgia	Univariable	4.170	3.768	4.614	< 0.001
Myalgia	Multivariable	2.723	2.427	3.055	< 0.001	< 0.001
Cough	Univariable	1.261	1.106	1.437	0.001
Cough	Multivariable	0.984	0.846	1.144	0.834	0.873
Dyspnea	Univariable	1.256	1.062	1.486	0.008
Dyspnea	Multivariable	0.831	0.691	0.999	0.049	0.087
Nasopharyngeal erythema	Univariable	1.681	1.468	1.925	< 0.001
Nasopharyngeal erythema	Multivariable	1.494	1.280	1.745	< 0.001	< 0.001
Gastrointestinal symptoms	Univariable	1.215	1.09	1.354	< 0.001
Gastrointestinal symptoms	Multivariable	1.174	1.043	1.321	0.008	0.018
Sample	Univariable	1.067	0.959	1.187	0.235
Confirmed infection	Univariable	1.01	0.842	1.212	0.914
A subtype	Univariable	1.046	0.895	1.223	0.573
B subtype	Univariable	1.088	0.872	1.358	0.456

CI Confidence interval, COPD Chronic obstructive pulmonary disease, FDR False discovery rate. Values in bold denotes statistical signification