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. 2024 Feb 6;16(1):2307542. doi: 10.1080/19490976.2024.2307542

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 7. — Groups: mice transplanted with normal human microbiota (F-N), GC microbiota (F-CA), pbs (F-MNU), and mice without induction and treatment (Control) (−6 + 36 w). (a) Immunohistochemical analysis of levels of the tumor-related indicators Ki-67 and CK-7 protein in gastric tissue of each group, together with the differential expression of GPR109A, HOPX, CD8, and IFN-γ proteins. (b-f) Quantification of the results of (A). (g) Western blotting of GPR109A, HOPX, CD8, and IFN-γ proteins in gastric tumor tissue of the different groups. (h) Quantification of the results of (G). n = 5 to 6 mice/group, cages = 2 to 3/group, cages = 2 to 3/group. Data indicate the mean ± SD. *p < .05, **p < .01, and ***p < .001, by 2-tailed Student’s t test or one-way ANOVA.