Table 3.
Caspase-3, caspase-8, Bax, and Bcl-2 levels of compounds 7j, 7k, and 7l.
Compd. no. | Caspase-3 |
Caspase-8 |
Bax |
Bcl-2 |
||||
---|---|---|---|---|---|---|---|---|
Conc (Pg/mL) | Fold change | Conc (ng/mL) | Fold change | Conc (Pg/mL) | Fold change | Conc (ng/mL) | Fold reduction | |
7j | 460 ± 4 | 7.0 | 2.00 | 22 | 291 | 32 | 0.95 | 5 |
7k | 530 ± 5 | 8.0 | 2.30 | 25 | 310 | 34 | 0.80 | 6 |
7l | 587 ± 5 | 9.0 | 2.55 | 28 | 362 | 40 | 0.60 | 8 |
Staurosporine | 465 ± 4 | 7.0 | 1.85 | 21 | 288 | 32 | 1.00 | 5 |
Control | 65 | 1.0 | 0.09 | 1 | 9 | 1 | 5.00 | 1 |