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. Author manuscript; available in PMC: 2024 Sep 24.
Published in final edited form as: J Physiol. 2023 May 21;602(18):4461–4486. doi: 10.1113/JP284538

Figure 8. Left ventricular expression of dyadic Ca2+ handling proteins and t-tubule regulators in the aortic constriction model.

Figure 8.

A, left panels: left ventricular mRNA levels of RyR, LTCC, and NCX in control and post-aortic constriction hearts. A, right panels: Representative Western blots and mean measurements of protein expression. B, expression of the t-tubule regulators JPH2, BIN1, DNM2, and MTM1 in the two experimental groups at the mRNA (left panels) and protein levels (right panels). Data are presented as mean ± SD, with P values indicated. Statistical comparisons vs. control were made by unpaired t test. For qPCR (all genes), n = 5 hearts for aortic constriction and control groups. For Western blots (all proteins), n = 6 hearts for the control group and n = 5 for aortic constriction group.