Table 6.
Arterial blood and hemodynamic values in the aortic constriction model
| Group | Day 0 | Day 7 | P vs. Day 7 control | |
|---|---|---|---|---|
|
| ||||
| pH | Control | 7.37 ± 0.03 | 7.37 ± 0.03 | |
| Aortic constriction | 7.35 ± 0.021 | 7.35 ± 0.02 | 0.179 | |
| PCO2 (mmHg) | Control | 49.9 ± 3.6 | 50.1 ± 3.8 | |
| Aortic constriction | 53.1 ± 3.0 | 52.8 ± 1.6 | 0.181 | |
| PO2 (mmHg) | Control | 20.9 ± 3.4 | 18.7 ± 4.0 | |
| Aortic constriction | 19.8 ± 2.6 | 21.6 ± 3.0 | 0.231 | |
| Haematocrit (%) | Control | 36.4 ± 3.6 | 38.1 ± 6.1 | |
| Aortic constriction | 36.8 ± 2.4 | 38 ± 5.4 | 0.979 | |
| Total haemoglobin (g/dl) | Control | 10.9 ± 0.9 | 11.6 ± 1.7 | |
| Aortic constriction | 11.1 ± 0.9 | 11.4 ± 1.5 | 0.848 | |
| O2 content (ml/100 ml) | Control | 8.6 ± 0.9 | 7.9 ± 1.3 | |
| Aortic constriction | 7.7 ± 1.7 | 8.4 ± 2.1 | 0.663 | |
| Aortic pressure (mmHg) | Control | 45.0 ± 2.9 | 47.5 ± 2.1 | |
| Aortic constriction | 44.0 ± 2.1 | 64.9 ± 9.7 | 0.004 | |
| Atrial pressure (mmHg) | Control | 2.0 ± 1.0 | 3.0 ± 1.1 | |
| Aortic constriction | 2.7 ± 0.8 | 2.8 ± 1.0 | 0.771 | |
| Heart rate (beats/min) | Control | 162 ± 5 | 152 ± 8 | |
| Aortic constriction | 170 ± 11 | 160 ± 12 | 0.250 | |
Values are presented at Day 0 and Day 7 of the intervention. Data presented as mean ± SD, with P values as indicated. Statistical comparisons were made vs. Controls using unpaired t test. n = 5 animals for both groups.