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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Graphic summary of the regulation and action of S100A6 during mouse implantation and decidualization. Blastocyst-derived lactate regulates S100A6 expression through the cPLA2/AA/COX2/PGI2/PPAR δ pathway. S100A6 regulates decidualization via the RAGE/EGFR/ERK pathway.