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. 2024 Jan 30;13(3):257. doi: 10.3390/cells13030257

Figure 7.

Figure 7

MAP kinase activation in the TRPM3-mutant human lens epithelial B3 (HLE-B3) cells and Trpm3-mutant mouse lenses. Quantitative immunoblot analysis of MAPK3/p44 and MAPK1/p42 in heterozygous TRPM3-I/M and homozygous TRPM3-M/M mutant HLE-B3 cell-lines (A–C) and in Trpm3-mutant mouse lenses at P21 (D–F). Constitutive MAPK3 and MAPK1 levels are shown in (A,D) (red bands) and in (B,E) (black and white bars). Phosphorylated (P) MAPK3 and MAPK1 levels are shown in (A,D) (green/yellow bands) and in (C,F) (black and white bars). WT, wild-type. M, molecular weight markers. * p < 0.05; ** p < 0.01; error bars ± SE.