STAT3α	Signal Transducer and Activator of Transcription 3α
STAT3β	Signal Transducer and Activator of Transcription 3β
STAT1	Signal Transducer and Activator of Transcription 1
STAT2	Signal Transducer and Activator of Transcription 2
STAT4	Signal Transducer and Activator of Transcription 4
STAT5a	Signal Transducer and Activator of Transcription 5a
STAT5b	Signal Transducer and Activator of Transcription 5b
STAT6	Signal Transducer and Activator of Transcription 6
NTD	N-terminal domain
CCD	Coiled-coil domain
DBD	DNA-binding domain
SH2	SRC-homology-2 domain
TAD	Carboxyl-terminal transactivation domain
IFN	Interferon
IL	Interleukin
JAK1	Janus kinase 1
JAK2	Janus kinase 2
Gp130	Glycoprotein 130
BCL6	B cell lymphoma protein 6
PI3K	Phosphoinositide 3 kinase pathways
MAPK	Mitogen activated protein kinase pathways
ERK	Extracellular receptor kinase pathways
EGF	Epidermal growth factor
FGF	Fibroblast growth factor
IGF	Insulin-like growth factor
Gp130	Glycoprotein 130
Tyr705	Tyrosine 705
PTPs	Protein tyrosine phosphatases
PIAS	Protein inhibitors of activated STAT
SOCS	Suppressors of cytokine signaling
SHP-1/2	Src homology region 2 domain-containing phosphatase 1 and 2
NSCLC	Non-small cell lung cancer
siRNA	Small interfering RNA
Rb	Retinoblastoma protein
EMT	Epithelial-to-mesenchymal transition
Twist1	Twist-related protein 1
bHLH	Basic helix-loop-helix
E-cadherin	Epithelial cadherin
N-cadherin	Neural cadherin
MMPs	Matrix metalloproteinases
HIF1α	Hypoxia-inducible factor-1α
VEGF	Vascular endothelial growth factor
PD-L1	Programmed death-ligand 1
NPCs	Neural precursor cells
PTC	Papillary thyroid carcinoma
TPO	Thyroid peroxidase
Snail1	Snail Family Transcriptional Repressor 1
GSK	Glycogen synthase kinase
HNSCCs	Head and neck squamous cell cancer cell lines
DLTs	Dose limiting toxicities
FDA	U.S. Food and Drug Administration
TUNEL	Transferase-mediated dUTP nick-end labeling
AML	Acute Myelogenous Leukemia
GVHD	Graft versus host disease
ORR	Objective response rate
OSCC	Oral squamous cell carcinoma
RT-PCR	Reverse transcription-polymerase chain reaction
ELISA	Enzyme-linked immunosorbent assay
TKIs	Tyrosine kinase inhibitors
HCC	Human hepatocellular carcinoma
HepPten−	Hepatocyte-specific deletion of Pten
cPR	Confirmed partial response
RECIST	Response Evaluation Criteria in Solid Tumors
CLL	Chronic Lymphocytic Lymphoma
BBI608	Napabucasin
SH2	Src homology region 2
Shp1	Domain-containing phosphatase 1
TKI258	Dovitinib
FGFR1	Fibroblast growth factor receptor 1
FGFR2	Fibroblast growth factor receptor 2
FGFR3	Fibroblast growth factor receptor 3
HBCx2	Xenograft model
siRNAs	Small interfering RNAs
shRNA	Short hairpin RNA
RNAi	RNA interference
dsRNA	Double stranded RNA
Gint4.T-STAT3	Glioblastoma a novel aptamer-siRNA chimera
BTK	Bruton tyrosine kinase
3′-UTR	3′-untranslated region
NHL	Non-Hodgkin’s Lymphoma
IDH	Isocitrate dehydrogenase enzyme
IDH1	Isocitrate dehydrogenase enzyme 1
IDH2	Isocitrate dehydrogenase enzyme 2