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. 2024 Feb 5;16(3):678. doi: 10.3390/cancers16030678

Figure 1.

Figure 1

Subtype changes between primary tumors and PLN. (A) Subtype concordance between primary tumor and positive lymph node in the tissue microarrays of 47 breast cancer patients. (B) Subtype concordance between primary tumor and positive lymph node in 64 breast cancer patients collected from the hospital. (C) Distribution of PAM50 intrinsic subtype in primary tumors versus PLN, n = 24. (D) The schematic picture of the popliteal lymph node metastasis model, n = 8. (E) The expression of estrogen receptor, progesterone receptor, and HER2 in footpad primary tumor in situ and its paired positive popliteal lymph node of nude mice. Top, 5× magnification (scale bar, 160 μm); bottom, 200× magnification (scale bar, 10 μm), n = 8. (F) The degree of ER, PR, and HER2 immunostaining in footpad primary tumor in situ and its paired positive popliteal lymph node of nude mice, n = 8.