Table 1.
Analyzing the differences in patients’ demographics between those with high PIV and low PIV.
| Characteristic | Total | Low PIV | High PIV | p |
|---|---|---|---|---|
| N = 193 | N = 99 (51.3) | N = 94 (48.7) | ||
| Age, median (IQR) | 78 (73–83) | 78 (73–83) | 79 (73–83) | 0.38 |
| Sex, n (%) | 0.07 | |||
| Male | 154 (79.7) | 84 (84.8) | 70 (74.7) | |
| Female | 39 (20.2) | 15 (15.1) | 24 (25.5) | |
| Smoke, n (%) | 149 (77.2) | 83 (83.8) | 66 (70.2) | 0.02 |
| Diabetes, n (%) | 31 (16.0) | 16 (16.1) | 15 (15.9) | 0.96 |
| Clinical T stage, n (%) | <0.001 | |||
| cTa | 67 (34.7) | 41 (41.4) | 26 (27.6) | |
| cTis | 24 (12.4) | 18 (12.3) | 6 (11.7) | |
| cT1 | 49 (25.3) | 23 (25.1) | 26 (23.9) | |
| cT2 | 29 (15.0) | 14 (14.9) | 15 (14.1) | |
| cT3 | 18 (9.3) | 3 (9.2) | 15 (8.8) | |
| cT4 | 6 (3.1) | 0 (3.1) | 6 (2.9) | |
| BMI, median (IQR) | 26 (24–29) | 26 (24–29) | 26 (24–28) | 0.39 |
| Surgical approach, n (%) | 0.27 | |||
| Open | 186 (96.3) | 94 (94.9) | 92 (97.8) | |
| Robot-assisted | 7 (3.6) | 5 (5.0) | 2 (2.1) | |
| Urinary diversion, n (%) | 0.003 | |||
| Ureterocutaneostomy | 21 (10.8) | 6 (6.0) | 15 (15.9) | |
| Ileal conduit | 148 (76.6) | 74 (78.2) | 74 (78.7) | |
| Orthotopic neobladder | 24 (12.4) | 19 (19.1) | 5 (5.3) | |
| Pathological T stage, n (%) | 0.001 | |||
| pT0 | 14 (7.2) | 10 (10.1) | 4 (4.2) | |
| pTa | 10 (5.1) | (5.0) | 5 (5.3) | |
| pTis | 23 (11.9) | 17 (17.1) | 6 (6.3) | |
| pT1 | 26 (13.4) | 19 (19.1) | 7 (7.4) | |
| pT2a | 30 (15.5) | 16 (16.1) | 14 (14.8) | |
| pT2b | 5 (2.5) | 3 (3.0) | 2 (2.1) | |
| pT3a | 49 (25.3) | 22 (22.2) | 27 (28.7) | |
| pT3b | 8 (4.1) | 4 (3.0) | 5 (5.3) | |
| pT4a | 21 (10.8) | 4 (4.0) | 17 (18.0) | |
| pT4b | 7 (3.6) | 0 (0.0) | 7 (7.4) | |
| Lymph node, n (%) | 37 (19.1) | 11 (11.1) | 26 (27.6) | 0.004 |
| LVI, n (%) | 128 (66.3) | 54 (54.5) | 74 (78.7) | <0.001 |
| Locally advanced disease, n (%) | 102 (52.8) | 37 (37.3) | 65 (69.1) | <0.001 |
| Adjuvant chemotherapy, n (%) | 40 (20.7) | 15 (15.1) | 25 (26.6) | 0.05 |
| Progressive disease, n (%) | 61 (31.6) | 22 (22.2) | 39 (41.4) | 0.004 |
| Cancer-related deaths, n (%) | 96 (49.7) | 44 (44.4) | 52 (55.3) | 0.131 |
| Any-cause deaths, n (%) | 52 (26.9) | 26 (26.2) | 26 (27.6) | 0.827 |
PIV = Pan-immune inflammation index; BMI = Body mass index; IQR = Interquartile range; LVI = lymph vascular infiltration.