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Canonical pathways of the complement activation and interaction of the coagulation system with the CS. Abbreviations. C1 INH, C1 inhibitor; DAF, decay-accelerating factor, or CD55, cluster of differentiation 55; C4BP, C4, binding protein; MCP, membrane cofactor protein, or CD46, cluster of differentiation 46; FH, factor H; FD, factor D; FI, factor I; MAC, membrane attack complex.
